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Analysis of institutional authors

Martinez-Manez, RamonAuthorSancenon, FelixAuthor

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October 12, 2024
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Not always what closes best opens better: mesoporous nanoparticles capped with organic gates

Publicated to: SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS. 20 (1): 699-709 - 2019-01-01 20(1), DOI: 10.1080/14686996.2019.1627173

Authors:

Anon, E.; Ana M. Costero; Gaviña, Pablo; MARGARITA PARRA ALVAREZ; El Haskouri, J.; Amorós, P.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix
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Affiliations

CIBER BBN, Madrid, Spain - Author
Univ Politecn Valencia, Dept Quim, Valencia, Spain - Author
Univ Valencia, Inst Ciencia Mat ICMUV, Valencia, Spain - Author
Univ Valencia, Univ Politecn Valencia, Inst Interuniv Invest Reconocimiento Mol & Desarr, Doctor Moliner 50, E-46100 Valencia, Spain - Author
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Abstract

Four types of calcined MCM-41 silica nanoparticles, loaded with dyes and capped with different gating ensembles are prepared and characterized. N1 and N2 nanoparticles are loaded with rhodamine 6G and capped with bulky poly(ethylene glycol) derivatives bearing ester groups (1 and 2). N3-N4 nanoparticles are loaded with sulforhodamine B and capped with self-immolative derivatives bearing ester moieties. In the absence of esterase enzyme negligible cargo release from N1, N3 and N4 nanoparticles is observed whereas a remarkable release for N2 is obtained most likely due to the formation of an irregular coating on the outer surface of the nanoparticles. In contrast, a marked delivery is found in N1, N3, and N4 in the presence of esterase enzyme. The delivery rate is related to the hydrophilic/hydrophobic character of the coating shell. The use of hydrophilic poly(ethylene glycol) derivatives as gating ensembles on N1 and N2 enables an easy access of esterase to the ester moieties with subsequent fast cargo release. On the other hand, the presence of a hydrophobic monolayer on N3 and N4 partially hinders esterase enzyme access to the ester groups and the rate of cargo release was decreased. [GRAPHICS] .
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Keywords

10 engineering and structural materials102 porous / nanoporous / nanostructured materialsControlled-releaseDeliveryDesignDrugEsterase controlled releasEsterase controlled releaseGated nanodevicesMesoporous nanoparticlesMesoporous nanoparticles,gated nanodevices,esterase controlled releasePeptidSilica nanoparticlesSupportsSystems

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2019, it was in position 63/314, thus managing to position itself as a Q1 (Primer Cuartil), in the category Materials Science, Multidisciplinary.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-02:

  • WoS: 3
  • Scopus: 4
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-02:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 19.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 19 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.
  • The number of mentions on the social network Facebook: 1 (Altmetric).
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
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Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Anon, Elena) and Last Author (Sancenón Galarza, Félix).

the author responsible for correspondence tasks has been Costero, Ana M.

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Awards linked to the item

We thank the Spanish Government, FEDER funds (MAT2015-64139-C4-4-R) and the Generalitat Valenciana (PROMETEOII/2014/047) for support and SCSIE (Universitat de Valencia) for the equipment employed. NMR was registered at the U26 facility of ICTS 'NANBIOSIS' at the Universitat of Valencia.
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