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Analysis of institutional authors

Vicente-Gomila, JmAuthor

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October 30, 2024
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The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials

Publicated to:Pesquisa Brasileira Em Odontopediatria E Clinica Integrada. 22 e210046- - 2022-01-01 22(), DOI: 10.1590/pboci.2022.011

Authors: Martins, ML; Leite, KLD; Magno, MB; Masterson, D; Vicente-Gomila, JM; Cavalcanti, YW; Maia, LC; Fonseca-Gonçalves, A

Affiliations

Univ Fed Paraiba, Dept Clin & Social Dent, Joao Pessoa - Author
Univ Fed Rio de Janeiro, Hlth Sci Ctr, Cent Lib, Rio De Janeiro - Author
Univ Fed Rio de Janeiro, Sch Dent, Dept Pediat Dent & Orthodont, Rio De Janeiro - Author
Univ Politecn Valencia, Dept Engn Projects - Author

Abstract

Objective: To describe and evaluate the xylitol products' applicability and its effects in the health area worldwide utilizing a bibliometric analysis from randomized controlled trials (RCT) with humans. Material and Methods: Electronic searches were carried out in Medline/PubMed, Scopus, Cochrane Library, Web of Science, and VHL databases. The main data extracted were: year, area of applicability, type of treatment, country, journal, xylitol posology and concentration, presentation form, outcomes, and effects. Results: From 1476 studies, 257 were included. These studies were published between 1973-2021. The majority was carried out in dentistry (78.9%) and under preventive treatment (67.4%). These studies were developed in the USA (15.4%) and published in Caries Research (6.6%). The posology and concentration ranged between 0.004-67 g/day and 0.002-100%, respectively. The xylitol is usually used in the chewing gum form (44.0%), and for antimicrobial activity evaluation (38.5%). A positive effect was observed in 204 studies (79.3%) and was associated with xylitol concentration >= 15% (p=0.007). Side effects were reported in 8.2% and were associated with posology >= 5 g/day (p=0.05). Conclusion: Most studies with xylitol were conducted to prevent diseases in the dentistry field. The chewing gum form and antimicrobial activity evaluation were more frequent. Most xylitol products have a positive effect, and few studies report side effects.

Keywords

Antimicrobial activityArticleBeverageBibliometricsBiofilmBowel motilityChewing gumChewing-gumChlorhexidineClinical outcomeClinical-trialDental cariesDental-cariesDentistryDouble-blindDry mouthFlurofamideGustatory stimulantsHumanIntervention studyMasticationMouth hygieneOtitis-mediaParenteral nutritionPeriodonticsProphylaxisQuality of lifeRandomized controlled trial (topic)Randomized controlled trials as topicSalivary mutans streptococciStomach emptyingSubsp lactis bb-12SucroseTherapeuticsTooth brushingXerostomiaXylitol

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Pesquisa Brasileira Em Odontopediatria E Clinica Integrada, Q3 Agency Scopus (SJR), its regional focus and specialization in Orthodontics, give it significant recognition in a specific niche of scientific knowledge at an international level.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2025-07-20:

  • WoS: 1
  • Scopus: 1

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-07-20:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 44 (PlumX).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.

Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Brazil.