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This research was carried out as part of the regional project NanoSerpa "Desarrollo de una aplicacion software app para el peritaje de riesgos derivados de la fabricacion de aplicacion de nanomateriales en entorno industriales y materiales de edificacion -IMINOD/2019/29", funded by the Valencian Institute of Business Competitiveness (IVACE).

Analysis of institutional authors

Colmenar González, InmaculadaAuthor
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Article

Nanosafety Analysis of Graphene-Based Polyester Resin Composites on a Life Cycle Perspective

Publicated to:Nanomaterials. 12 (12): 2036- - 2022-06-01 12(12), DOI: 10.3390/nano12122036

Authors: Aznar Molla, Francisco; Heredia Alvaro, Jose Antonio; Andreu Sanchez, Oscar; Fito-Lopez, Carlos; Colmenar Gonzalez, Inmaculada

Affiliations

Technol Inst Packaging Transport & Logist, ITENE, Valencia 46001, Spain - Author
Univ Jaume I Castellon, Ind Chair Director 4 0, Castellon De La Plana 12071, Spain - Author
Univ Jaume I Castellon, Res Line Sustainable Chem & Supramol Chem, Castellon De La Plana 12071, Spain - Author
Univ Valencia, Fac Biol Sci, Dept Cellular Biol Funct Biol & Phys Anthropol, Lab Ecotoxicol & Environm Qual, Dr Moliner 50, Valencia 46100, Spain - Author

Abstract

The use, production, and disposal of engineering nanomaterials (ENMs), including graphene-related materials (GRMs), raise concerns and questions about possible adverse effects on human health and the environment, considering the lack of harmonized toxicological data on ENMs and the ability of these materials to be released into the air, soil, or water during common industrial processes and/or accidental events. Within this context, the potential release of graphene particles, their agglomerates, and aggregates (NOAA) as a result of sanding of a battery of graphene-based polyester resin composite samples intended to be used in a building was examined. The analyzed samples were exposed to different weathering conditions to evaluate the influence of the weathering process on the morphology and size distribution of the particles released. Sanding studies were conducted in a tailored designed sanding bench connected to time and size resolving measurement devices. Particle size distributions and particle number concentration were assessed using an optical particle counter (OPC) and a condensation particle counter (CPC), respectively, during the sanding operation. A scanning electron microscope/energy dispersive X-ray (SEM/EDX) analysis was performed to adequately characterize the morphology, size, and chemical composition of the released particles. A toxicity screening study of pristine and graphene-based nanocomposites released using the aquatic macroinvertebrate Daphnia magna and relevant human cell lines was conducted to support risk assessment and decision making. The results show a significant release of nanoscale materials during machining operations, including differences attributed to the % of graphene and weathering conditions. The cell line tests demonstrated a higher effect in the human colon carcinoma cell line Caco2 than in the human fibroblasts (A549 cell line), which means that composites released to the environment could have an impact on human health and biota.

Keywords
EcotoxicityGraphenGrapheneNanomaterialNanoparticleNanotechnologyRisk assessment

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Nanomaterials due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2022, it was in position 39/160, thus managing to position itself as a Q1 (Primer Cuartil), in the category Physics, Applied.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2025-04-29:

  • WoS: 3
  • Scopus: 3
  • Europe PMC: 1
  • OpenCitations: 2
Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-04-29:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 11.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 11 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 0.5.
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: Last Author (Colmenar González, Inmaculada).