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Analysis of institutional authors

Carceller-Carceller, Jose MiguelAuthorCliment, MjAuthorIborra, SCorresponding AuthorCorma, ACorresponding Author

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October 30, 2024
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Production of chiral alcohols from racemic mixtures by integrated heterogeneous chemoenzymatic catalysis in fixed bed continuous operation

Publicated to: Green Chemistry. 22 (9): 2767-2777 - 2020-05-07 22(9), DOI: 10.1039/c9gc04127c

Authors:

Carcelter, JM; Mifsud, M; Climent, MJ; Iborra, S; Corma, A
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Affiliations

Univ Politecn Valencia, Inst Tecnol Quim, Avda Naranjos S-N - Author

Abstract

Valuable chiral alcohols have been obtained from racemic mixtures with an integrated heterogeneous chemoenzymatic catalyst in a two consecutive fixed catalytic bed continuous reactor system. In the first bed the racemic mixture of alcohols is oxidized to the prochiral ketone with a Zr-Beta zeolite and using acetone as the hydrogen acceptor. In the second catalytic bed the prochiral ketone is stereoselectively reduced with an alcohol dehydrogenase (ADH) immobilized on a two dimensional (2D) zeolite. In this process, the alcohol (isopropanol) formed by the reduction of acetone in the first step reduces the cofactor in the second step, and the full reaction cycle is in this way internally closed with 100% atom economy. A conversion of about 95% with similar to 100% selectivity to either the (R) or the (S) alcohol has been obtained for a variety of racemic mixtures of alcohols.
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Keywords

AcetoneAlcohol dehydrogenaseContinuous operationContinuous reactorsDehydrogenaseDeracemisationDynamic kinetic resolutionHydrogen acceptorImmobilizationMeerwein-ponndorf-verleyMixturesOxidationProchiral ketonesRacemic mixturesReaction cyclesReductionSecondary alcoholsSn-betaTwo dimensional (2 d)Zeolite-betaZeolites

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Green Chemistry due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2020, it was in position 2/44, thus managing to position itself as a Q1 (Primer Cuartil), in the category Green & Sustainable Science & Technology. Notably, the journal is positioned above the 90th percentile.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2025-12-27:

  • WoS: 22
  • Scopus: 27
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-12-27:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 42 (PlumX).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
  • Assignment of a Handle/URN as an identifier within the deposit in the Institutional Repository: http://hdl.handle.net/10251/168620
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Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Carcelter, JM) and Last Author (Corma Canós, Avelino).

the authors responsible for correspondence tasks have been Iborra Chornet, Sara and Corma Canós, Avelino.

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Awards linked to the item

The research leading to these results has received funding from the Spanish Ministry of Science, Innovation and Universities through "Severo Ochoa" Excellence Programme (SEV-2016-0683) and the PGC2018-097277-B-100(MCIU/AEI/FEDER, UE) project. J. M. C. thanks to Universitat Politecnica de Valencia for a predoctoral fellowship.
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