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Analysis of institutional authors

Garcia H.AuthorGarcia, HermenegildoCorresponding Author

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January 31, 2025
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Review
Green

Hydrogenation of amides to amines by heterogeneous catalysis: a review

Publicated to: Green Chemistry. 26 (5): 2341-2364 - 2023-12-16 26(5), DOI: 10.1039/d3gc04175a

Authors:

Yang, Huiru; Garcia, Hermenegildo; Hu, Changwei
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Affiliations

Inst Univ Tecnol Quim, CSIC, Consejo Super Invest Cient, Av Naranjos S-N, Valencia 46022, Spain - Author
Sichuan Univ, Coll Chem, Key Lab Green Chem & Technol, Minist Educ, Chengdu 610064, Peoples R China - Author

Abstract

Amines are pivotal building blocks for a range of applications, including pharmaceuticals, polymers, agrochemicals, and organic synthesis. The hydrogenation of amides using molecular hydrogen via heterogeneous catalysis is considered a promising method for producing amines with considerably high atom efficiency, environmental friendliness, and eonomic viability. Continued developments have occurred in this area, with milestones reached in the hydrogenation of various amides to amines via heterogeneous catalysis. At present, no systematic analysis of the influence of amide structures on their reactivity and the required type of catalyst has been reported. This review describes the most recent advances in catalytic amide hydrogenation, paying special attention to the influence of structural features (cyclic amides and aliphatic acyclic amides) on catalyst performance. Structural features endow amides with specific reactivities, reflected in considerable differences in the ease of hydrogenation and diverse product selectivity. In addition, insights into the conversion of polyamides, fatty acids, and triglycerides to amines are provided. This review provides new perspectives for designing and applying heterogeneous catalysts adapted to specific conditions and amide structures. A comprehensive summary of heterogeneous catalysts for the hydrogention of various amides with differnent structural feactures to amines.
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Keywords

AciAgricultural chemicalsAlcoholsAlkyl-aryl ketonesAmide structuresAmidesAminesAmmoniaAtom efficiencyBuilding blockesCatalysisCatalystsEfficientEnvironmental friendlinessFatty acidsHydrogenationMolecular hydrogenN-methylationOrganic polymersOrganic synthesisPharmaceutical synthesisPolymer synthesisReductive aminationSecondarySelective hydrogenationStructural featureSystematic analysisTertiary amides

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Green Chemistry due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2023, it was in position 32/231, thus managing to position itself as a Q1 (Primer Cuartil), in the category Chemistry, Multidisciplinary.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 1.14. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 13, 2025)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Weighted Average of Normalized Impact by the Scopus agency: 1.27 (source consulted: FECYT Mar 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2026-01-21, the following number of citations:

  • WoS: 10
  • Scopus: 16
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-01-21:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 16 (PlumX).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
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Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: China.

the author responsible for correspondence tasks has been García Gómez, Hermenegildo.

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Awards linked to the item

This work was financially supported by the National Natural Science Foundation of China (No. 21536007) and the 111 Project (B17030). Financial support by the Spanish Ministry of Science and Innovation (CEX-2021-001230-S and PDI2021-0126071-OB-CO21 funded by MCIN/AEI/10.13039/501100011033) and Generalitat Valenciana (Prometeo 2021/038 and Advanced Materials programme Graphica MFA/2022/023 with funding from European Union NextGeneration EU PRTR-C17.I1) is gratefully acknowledged. Huiru Yang also acknowledges the support from the China Scholarship Council (CSC No. 202206240141).
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