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Analysis of institutional authors

Junquera-Godoy, IAuthorMartinez-De-Juan, J LAuthorLorente, G GonzalezAuthorGomis-Tena, JAuthorSaiz, JAuthorPrats-Boluda, GCorresponding Author

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June 2, 2025
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Assessment of the intermuscular coherence for the early detection of diabetic peripheral neuropathy: a cross-sectional study

Publicated to: Biocybernetics and Biomedical Engineering. 45 (3): 305-318 - 2025-01-01 45(3), DOI: 10.1016/j.bbe.2025.05.003

Authors:

Junquera-Godoy, Isabel; Martínez-de-Juan, José L.; González-Lorente, Gemma; Carot Sierra, José Miguel; Gomis-Tena Dolz, Julio; Saiz Rodríguez, Francisco Javier; Mas-Penalva, Gema Concepción; Soler-Climent, Esther; Prats-Boluda, Gema
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Affiliations

Hosp Gen FISABIO, Area Invest Enfermeria Fisioterapia, Dept Salud Elche, Elche, Spain - Author
Hosp Gen Univ Elche, Serv Rehabil, FISABIO, Elche, Spain - Author
Univ Politecn Valencia, Ctr Invest & Innovac Bioingn CI2B, Valencia, Spain - Author
Univ Politecn Valencia, Dept Estat Invest Operat Aplicadas & Calidad, Valencia, Spain - Author
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Abstract

Diabetes mellitus (DM) is a global epidemic marked by chronic hyperglycaemia due to insulin insufficiency or resistance. Diabetic peripheral neuropathy (DPN) is a common complication of diabetes, affecting up to 50 % of patients. It typically presents as a distal, symmetric, length-dependent neuropathy. Early detection of DPN is crucial to mitigate its impact on quality of life and healthcare costs. While current diagnostic methods like nerve conduction studies have limitations, surface electromyography (sEMG) shows promise for its non-invasive, realtime neuromuscular assessments. This study explores the potential of sEMG, particularly through intermuscular coherence, to serve as a sensitive biomarker for early DPN detection. Two coherence parameters, partial coherence (PC) and partial directed coherence (PDC), based on the Multivariate Autoregressive (MVAR) models have been analysed in three population groups: 33 healthy volunteers (CT), 10 diabetic patients with a low risk of DPN (LW), and 17 moderate/high-risk patients (MH). In early-stage DPN, synergistic muscle pairs showed increased PC and PDC values compared to controls, likely due to neuronal hyperexcitability and compensatory mechanisms within the nervous system. In contrast, advanced DPN stages exhibited reduced coherence, reflecting nerve fiber loss and central nervous system (CNS) impairment, possibly exacerbated by structural CNS changes like spinal cord atrophy, affecting neural plasticity and adaptation. Our study found that the dorsiflexor muscle pair, especially in the bandwidth 10-50 Hz of the PDC parameter, effectively discriminated between DPN stages, distinguishing all three groups with statistical significance. This suggests its potential as an early detection biomarker for DPN and for monitoring disease progression.
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Keywords

ActivationBiomarkerComplexityDiabetic peripheral neuropathyElectromyographyEmgFibersIntermuscular coherencIntermuscular coherenceMotor cortexMultimuscle controlMuscle interactionPatternsSkeletal-muscleStanc

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Biocybernetics and Biomedical Engineering due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2025, it was in position 20/124, thus managing to position itself as a Q1 (Primer Cuartil), in the category Engineering, Biomedical.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-03:

  • WoS: 1
  • Scopus: 1
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-03:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 17 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

    It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

    • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
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    Leadership analysis of institutional authors

    There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Junquera Godoy, Isabel) and Last Author (Prats Boluda, Gema).

    the author responsible for correspondence tasks has been Prats Boluda, Gema.

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    Awards linked to the item

    This study was supported by grants from the Agencia Valenciana de la Innovacio (INNEST/2021/365) and the promoter POLISABIO (POLI-SABIO22_AP05) . Funding for the open-access publication charge was provided by CRUE-Universitat Politecnica de Valencia.
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