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Analysis of institutional authors

Ferrus, ACorresponding Author

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August 7, 2025
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Tachykinin-related peptides modulate odor perception and locomotor activity in Drosophila

Publicated to: MOLECULAR AND CELLULAR NEUROSCIENCE. 31 (3): 399-406 - 2006-03-01 31(3), DOI: 10.1016/j.mcn.2005.10.010

Authors:

Winther, ÅME; Acebes, A; Ferrús, A
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Affiliations

- Author

Abstract

The invertebrate tachykinin-related peptides (TKRPs) constitute a conserved family, structurally related to the mammalian tachykinins, including members such as substance P and neurokinins A and B. Although their expression has been documented in the brains of insects and mammals, their neural functions remain largely unknown, particularly in behavior. Here, we have studied the role of TKRPs in Drosophila. We have analyzed the olfactory perception and the locomotor activity of individuals in which TKRPs are eliminated in the nervous system specifically, by using RNAi constructs to silence gene expression. The perception of specific odorants and concentrations is modified towards a loss of sensitivity, thus resulting in a significant change of the behavioral response towards indifference. In locomotion assays, the TKRP-deficient flies show hyperactivity. We conclude that these peptides are modulators of olfactory perception and locomotion activity in agreement with their abundant expression in the olfactory lobes and central complex. In these brain centers, TKRPs seem to enhance the regulatory inhibition of the neurons in which they are expressed. (c) 2005 Elsevier Inc. All rights reserved.
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Keywords

Antennal lobeBehaviorBrainCentral body complexCentral complexDrosophilaExpressionLocomotioMelanogasterNervous-systemNeuronsNeuropeptideOlfactionReceptorRnRna interferenceSubstance-p

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal MOLECULAR AND CELLULAR NEUROSCIENCE due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2006, it was in position 36/200, thus managing to position itself as a Q1 (Primer Cuartil), in the category Neurosciences.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-03:

  • WoS: 97
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-03:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 139 (PlumX).
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Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: Last Author (Ferrús Pérez, Mª Antonia).

the author responsible for correspondence tasks has been Ferrús Pérez, Mª Antonia.

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